Search Results
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Building a Resilient Workforce
Every job can lead to stress. How people cope with that stress can be influenced by many factors. The Department of Homeland Security (DHS) employs a diverse staff that includes emergency responders, border patrol agents, federal air marshals, and policy analysts. These employees may be exposed t... More
Language: ENGCopyright: 2012 -
Review of NASA's Human Research Program Evidence Books: A Letter Report
At the request of NASA, an IOM committee reviewed NASA Human Research Program's (HRP's) Scientific Merit Assessment Processes for directed research. Directed research is commissioned or noncompetitively awarded research that is not competitively solicited because of specific reasons, such as time li... More
Language: ENGCopyright: 2008 -
Examining the State of the Science of Mammalian Embryo Model Systems: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionBecause of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the sci... More
Language: ENGCopyright: 2020 -
An Examination of Emerging Bioethical Issues in Biomedical Research: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionOn February 26, 2020, the Board on Health Sciences Policy of the National Academies of Sciences, Engineering, and Medicine hosted a 1-day public workshop in Washington, DC, to examine current and emerging bioethical issues that might arise in the context of biomedical research and to consider resear... More
Language: ENGCopyright: 2020 -
Current Issues in the Assessment of Respiratory Protective Devices for Occupational and Non-Occupational Uses: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionTo address approaches to the respirator approval process in the current landscape for both occupational and non-occupational use of respirators, the National Academies of Sciences, Engineering, and Medicine̱s Standing Committee on Personal Protective Equipment for Workplace Safety and Health convene... More
Language: ENGCopyright: 2020 -
Exploring Disaster Human Services for Children and Youth: From Hurricane Katrina To The Paradise Wildfires: Proceedings Of A Workshop Series
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionTo explore issues related to the effects of disasters on children and youth and lessons learned from experiences during previous disasters, the virtual workshop From Hurricane Katrina to Paradise Wildfires, Exploring Themes in Disaster Human Services was convened on July 22 and 23, 2020, by the Nati... More
Language: ENGCopyright: 2021 -
Building Resilience into the Nation’s Medical Product Supply Chains
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionOver the past several decades, supply chain disruptions have repeatedly plagued the U.S. health care system, costing health care systems millions of dollars per year, threatening the clinical research enterprise, and most importantly, imperiling the health and lives of patients. The Committee on Sec... More
Language: ENGCopyright: 2022 -
Applying Systems Thinking to Regenerative Medicine: Proceedings of a Workshop
Regenerative medicine products, which are intended to repair or replace damaged cells or tissues in the body, include a range of therapeutic approaches such as cell- and gene-based therapies, engineered tissues, and non-biologic constructs. The current approach to characterizing the quality of a reg... More
Language: ENGCopyright: 2021 -
Exploring Novel Clinical Trial Designs for Gene-Based Therapies: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Forum on Regenerative MedicineRecognizing the potential design complexities and ethical issues associated with clinical trials for genetherapies, the Forum on Regenerative Medicineof the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the worksh... More
Language: ENGCopyright: 2020 -
Understanding the Role of the Immune System in Improving Tissue Regeneration: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Forum on Regenerative MedicineThe Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve ou... More
Language: ENGCopyright: 2022 -
Strengthening a Workforce for Innovative Regulatory Science in Therapeutics Development
by Institute of Medicine • Steve Olson • Forum on Drug Discovery, Development, and Translation • Anne B. Claiborne • Board on Health Sciences PolicyThe development and application of regulatory science - which FDA has defined as the science of developing new tools, standards, and approaches to assess the safety, efficacy, quality, and performance of FDA-regulated products - calls for a well-trained, scientifically engaged, and motivated workfor... More
Language: ENGCopyright: 2011 -
Envisioning a Transformed Clinical Trials Enterprise in the United States
by Development • Anne B. Claiborne • Board on Health Sciences Policy • Rebecca A. English • Neil Weisfeld • Rapporteurs • Forum on Drug Discovery • TranslationThere is growing recognition that the United States' clinical trials enterprise (CTE) faces great challenges. There is a gap between what is desired - where medical care is provided solely based on high quality evidence - and the reality - where there is limited capacity to generate timely and prac... More
Language: ENGCopyright: 2012 -
International Regulatory Harmonization Amid Globalization of Drug Development
by Institute of Medicine • Victoria Weisfeld • Board on Health Sciences Policy • Tracy A. Lustig • Forum on Drug Discovery, Development, and TransitionThe past several decades have been a time of rapid globalization in the development, manufacture, marketing, and distribution of medical products and technologies. Increasingly, research on the safety and effectiveness of new drugs is being conducted in countries with little experience in regulation... More
Language: ENGCopyright: 2012 -
Crisis Standards of Care
by Institute of Medicine • Committee on Crisis Standards of Care: A Toolkit for indicators and Triggers • Board on Health Sciences PolicyDisasters and public health emergencies can stress health care systems to the breaking point and disrupt delivery of vital medical services. During such crises, hospitals and long-term care facilities may be without power; trained staff, ambulances, medical supplies and beds could be in short supply... More
Language: ENGCopyright: 2013 -
Neurodegeneration
by Institute of Medicine • Clare Stroud • Board on Health Sciences Policy • Forum on Neuroscience and Nervous System Disorders • Miriam DavisNeurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine\'s (IOM\'s) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson'... More
Language: ENGCopyright: 2013 -
A Ready and Resilient Workforce for the Department of Homeland Security
by Institute of Medicine • Board on Health Sciences Policy • Committee on the Department of Homeland Security Workforce ResilienceThe responsibilities of the Department of Homeland Security (DHS) range from preventing foreign and domestic terrorist attacks; securing the nation's borders; safeguarding transportation systems; responding to natural disasters; nuclear detection; and more. Created in 2002 from a merger that rapidly... More
Language: ENGCopyright: 2013 -
Discussion Framework for Clinical Trial Data Sharing
by Institute of Medicine • Board on Health Sciences Policy • Committee on Strategies for Responsible Sharing of Clinical Trial DataSharing data generated through the conduct of clinical trials offers the promise of placing evidence about the safety and efficacy of therapies and clinical interventions on a firmer basis and enhancing the benefits of clinical trials. Ultimately, such data sharing - if carried out appropriately - c... More
Language: ENGCopyright: 2014 -
Crisis Standards of Care: Ten Years Of Successes And Challenges: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Forum on Medical and Public Health Preparedness for Disasters and EmergenciesIn 2009 the Institute of Medicine (IOM) began to assess the need for better-defined medical and public health crisis standards of care (CSC) for catastrophic disasters and public health emergencies. Over the next 10 years, the IOM defined templates for those stakeholders responsible for integrated C... More
Language: ENGCopyright: 2021 -
Evolving Crisis Standards of Care and Ongoing Lessons from COVID-19: Proceedings Of A Workshop Series
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Forum on Medical and Public Health Preparedness for Disasters and EmergenciesCrisis Standards of Care (CSC) inform decisions on medical care during a large-scale crisis such as a pandemic or natural disaster, eliminating the need to make these decisions at the bedside without protections or guidance. Numerous points throughout the COVID-19 pandemic have demonstrated the nece... More
Language: ENGCopyright: 2022 -
Genome-Based Diagnostics
by Institute of Medicine • Steve Olson • Board on Health Sciences Policy • Adam C. Berger • Roundtable on Translating Genomic-Based Research for Health • Center for Medical Technology PolicyGenome-Based Diagnostics: Demonstrating Clinical Utility in Oncology is the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for furthe... More
Language: ENGCopyright: 2013 -
Exploring the Current Landscape of Consumer Genomics: Proceedings Of A Workshop
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Roundtable on Genomics and Precision HealthConsumer genomics, encompassing both direct-to-consumer applications (i.e., genetic testing that is accessed by a consumer directly from a commercial company apart from a health care provider) and consumer-driven genetic testing (i.e., genetic testing ordered by a health care provider in response to... More
Language: ENGCopyright: 2020 -
Ensuring an Effective Public Health Emergency Medical Countermeasures Enterprise
by Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Committee on Reviewing the Public Health Emergency Medical Countermeasures EnterpriseThe U.S. medical countermeasures (MCMs) enterprise is interconnected, complex, and dynamic. It includes public and private entities that develop and manufacture new and existing MCMs, ensure procurement, storage, and distribution of MCMs, and administer, monitor, and evaluate MCMs. The interagency g... More
Language: ENGCopyright: 2021 -
Sex Differences in Brain Disorders: Emerging Transcriptomic Evidence: Proceedings of a Workshop
by Board on Health Sciences Policy • Forum on Neuroscience and Nervous System Disorders • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionAccumulating evidence gathered over the past three decades has demonstrated a biological basis for differences between men and women with respect to clinical features and treatment responses to several neuropsychiatric, neurodevelopmental, and neurodegenerative disorders. Dramatic sex differences ha... More
Language: ENGCopyright: 2021 -
Novel Molecular Targets for Mood Disorders and Psychosis: Proceedings Of A Workshop
by Board on Health Sciences Policy • Forum on Neuroscience and Nervous System Disorders • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionMood disorders - including depression and bipolar disorder - are common, disabling, and potentially lethal disorders, characterized by a shortened lifespan from comorbid medical illness and rising suicide rates. Medications for these conditions have been shown to be insufficiently effective in the m... More
Language: ENGCopyright: 2021 -
Innovation in Drug Research and Development for Prevalent Chronic Diseases: Proceedings of a Workshop
by Forum on Drug Discovery, Development, and Translation • Board on Health Sciences Policy • National Academies of Sciences, Engineering, and Medicine • Health and Medicine DivisionInvestment and innovation in drug research and development (R&D) for highly prevalent chronic diseases has stalled in recent decades, despite half of all Americans living with at least one chronic disease. As a result, prevalent chronic diseases are producing immense health care costs as well as pre... More
Language: ENGCopyright: 2021